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| 2010 |
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2000-01
Ševčík J, Vičar J, Ulrichová J, Válka I, Lemr K, Šimánek V (2000) Capillary electrophoretic determination of sanguinarine and chelerythrine in plant extracts and pharmaceutical preparations. J Chromatogr A 866(2):293-298.
Křen V, Ulrichová J, Kosina P, Stevenson D, Sedmera P, Přikrylová V, Halada P, Šimánek V (2000) Chemoenzymatic preparation of silybin b-glucuronides and their biological evaluation. Drug Metab Dispos 28:1513-1517.
Škottová N, Krečman V, Váňa P, Chmela Z, Ulrichová J, Šimánek V (2000) Effect of silymarin and silibinin-phosphatidylcholine complex on plasma and lipoprotein cholesterol, and oxidation of LDL in rats fen on high cholestetrol diet supplemented with currant oil. Biomed Papers 144:55-58.
Simanek V, Kren V, Ulrichova J, Vicar J, Cvak L. (2000) Silymarin: What is in the name...? An appeal for a change of editorial policy. Hepatology 32:442-444.
Kosina P, Bartek J (2000) Determination of silybin in blood plasma using high performance liquid chromatography with solid phase extraction. Chem Listy 94:1115-1117.
Dvořák Z, Ulrichová J, Modrianský M, Maurel P (2000) Effect of colchicine and its derivatives on the expression of selected isoforms of cytochrome P 450 in primary cultures of human hepatocytes. Acta Universitatis Palackianae Olomucensis 143:47-50.
Modriansky M, Ulrichova J, Bachleda P, Anzenbacher P, Anzenbacherova E, Walterova D, Simanek V (2000) Human hepatocyte--a model for toxicological studies. Functional and biochemical characterization. Gen Physiol Biophys 19:223-235.
| 2001 |
Ulrichová J, Dvořák Z, Vičar J, Lata J, Smržová J, Šedo A, Šimánek V (2001) Cytotoxicity of natural compounds in hepatocyte cell culture models. The case of quarternary benzo[c]phenanthridine alkaloids. Toxicol Lett 125:125-132.
Šimánek V, Škottová N, Bartek J, Psotová J, Kosina P, Balejová L, Ulrichová J (2001) Extract from Silybum marianum as nutraceutical: a double blind placebo-controlled study in healthy young men. Czech J Food Sci 19:106-110.
Šimánek V, Škottová N, Ulrichová J: Perspective nutraceutical - Milk Thistle extract with polyunsaturated fatty acids. In Biologically-active Phytochemicals in Food (Pfannhauser W., Fenwick G.R., Khokhar S., eds), Thomas Graham House, Cambridge, pp.65-68, 2001.
Škottová N, Švagera Z, Večeřa R, Urbánek K, Jegorov A, Šimánek V (2001) Pharmacokinetic study of iodine labeled silibinins in rat. Pharmacol Res 44:247-253.
Šimánek V, Walterová D, Vičar J, Urbaníková J, Křen V, Modrianský M, Škottová N, Ulrichová J (2001) „Silymarin“ - Extrakt z Ostropestřce mariánského (Silybum marianum) – lék nebo potravní doplněk? Česká a Slov farmacie 50:66-69.
Kubisch J, Sedmera P, Halada P, Gažák R, Škottová N, Šimánek V, Křen V (2001) Chemoenzymatic preparation of oligoglycosides of silybin, the flavonolignan from Silybum marianum. Heterocycles 54:901-915.
Psotová J, Zahálková J, Hrbáč J, Šimánek V, Bartek J (2001) Determination of total antioxidant capacity in plasma by cyclic voltammetry. Two case reports. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 145:81-83.
Souček P, Zuber R, Anzenbacherová E, Anzenbacher P, Guengerich FP (2001) Minipig cytochromes P450 3A, 2A and 2C have similar properties to their human orthologs. BMC Pharmacology 1:11.
Anzenbacher, P, Anzenbacherová, E (2001) Cytochromes P450 and metabolism of xenobiotics. Cell Mol Life Sci 58:737-747.
Cervenkova K, Belejova M, Vesely J, Chmela Z, Rypka M, Ulrichova J, Modriansky M, Maurel P (2001) Cell suspensions, cell cultures, and tissue slices--important metabolic in vitro systems. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 145:57-60.
Smržová J, Dvořák Z, Lata J, Dítě P, Machala M, Bláha L, Šimánek V, Ulrichová J (2001) Optimisation of porcine hepatocyte cryopreservation by comparasion of viability and enzymatic activity of fresh and cryopreservated cells. Acta Vet Brno 70:141-147.
Smržová J, Ulrichová J, Dítě P, Lata J (2001) Transplantace hepatocytů – současný stav a výhled do budoucna. Vnitřní lékařství 47:790-796.
Gavenda A, Ševčík J, Psotová J, Bednář P, Barták P, Adamovský P, Šimánek V (2001) Determination of anthracycline antibiotics doxorubicin and daunorubicin by capillary electrophoresis with UV absorption detection. Electrophoresis 22:2782-2785.
Gavenda A, Bednář P, Barták P, Adamovský P, Ševčík J, Panagiotis T, Ulrichová J (2001) Estimation of partition coefficients by MEKC Part I: Potential pharmaceuticals based on 2-quinolone and 2-indolone. J Sep Sci 24:723-728.
Stejskal, D, Žurek, Švecová R, Zapletalová J, Bartek J, Oral I, Horalík D, Lačňák B, Jedelský L, Lenobelová H (2001) Využití analýzy kostního izoenzymu kyselé fosfatázy 5b u pacientů s osteopenií a osteoporózou (pilotní studie). Vnitřní Lékařství 47:60-62.
Chlopčíková Š, Psotová J, Miketová P (2001) Neonatal rat cardiomyocytes--a model for the study of morphological, biochemical and electrophysiological characteristics of the heart. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 145:49-55.
Valentová K, Frček J, Ulrichová J (2001) Jakon (Smallanthus sonchifolius) a Maka (Lepidium meyenii), tradiční andské plodiny na evropském trhu. Chem Listy 95:594-601.
| 2002 |
Šedo A, Vlašicová K, Barták P, Vespalec R, Vičar J, Šimánek V, Ulrichová J (2002) Quaternary benzo[c]phenanthridine alkaloids as inhibitors of aminopeptidase N and dipeptidyl peptidase IV. Phytother Res 16:84-87.
Stiborová M, Šimánek V, Frei E, Hobza P, Ulrichová J (2002) DNA adduct formation from quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine as revealed by the 32P-postlabeling technique. Chem-Biol Interact 140:213-242.
Kosina P, Křen V, Gebhardt R, Grambal F, Ulrichová J, Walterová D (2002) Antioxidant properties of silybin glycosides. Phytother Res 16:S33-S39.
Psotová J, Chlopčíková Š, Grambal F, Šimánek V, Ulrichová J (2002) Influence of silymarin and its flavonolignans on doxorubucin-iron induced lipid peroxidation in rat heart microsomes and mitochondria in comparison with quercetin. Phytother Res 16:S63-S67.
Zuber R, Modrianský M, Dvořák Z, Rohovský P, Ulrichová J, Šimánek V, Anzenbacher P (2002) Effect of silybin and its congeners on human liver microsomal cytochrome P450 activities. Phytother Res 16:632-638
Psotová, J., Chlopčíková, Š., Miketová, P. (2002) Can dextrazoxane be replaced by silibinin in the athracycline antibiotics therapy? Comparative study in rat cardiomyocytes. In XI. Biennial Meeting of the Society for Free Radical Research International. Pasquier C (ed.) Monduzzi Editore S.p.A. Medimond Inc. 711-715.
Dvořák Z, Ulrichová J, Pichard-Garcia L, Modrianský M, Maurel P (2002) Comparative effect of colchicine and colchiceine on cytotoxicity and CYP gene expression in primary human hepatocytes. Toxicol in Vitro 16:219-227.
Modriansky M, Tyurina YY, Tyurin VA, Matsura T, Shvedova AA, Yalowich JC, Kagan VE (2002) Anti-/pro-oxidant effects of phenolic compounds in cells: are colchicine metabolites chain-breaking antioxidants? Toxicology 177:105-117.
Anzenbacher P, Anzenbacherová E, Zuber R, Souček P, Guengerich FP (2002) Pig and minipig cytochromes P450. Drug Metab Dispos 30:100-102.
Zuber R, Anzenbacherová E, Anzenbacher P (2002) Cytochromes P450 and experimental models of drug metabolism. J Cell Mol Med 6:189-198.
2002-11
Vrba J, Modrianský M (2002) Oxidative burst of Kupfer cells: Target for liver injury treatment. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 146:15-20.
Stejskal D, Prošková J, Adamovská S, Juráková R, Bartek J (2002) Preliminary experience with resistin assessment in common population. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 146:47-49.
Arroyo A, Modriansky M, Serinkan FB, Bello RI, Matsura T, Jiang J, Tyurin VA, Tyurina YY, Fadeel B, Kagan VE (2002). NADPH oxidase-dependent oxidation and externalization of phosphatidylserine during apoptosis in Me2SO-differentiated HL-60 cells. Role in phagocytic clearance. J Biol Chem 277:49965-49975.
| 2003 |
Vespalec R, Barták P, Šimánek V, Vlčková M (2003) Electrophoretic investigation of interactions of sanguinarine and chelerythrine with molecules containing mercapto group. J Chromatogr B 797:357-366.
2003-02
Barták P, Šimánek V, Vlčková M, Ulrichová J, Vespalec R (2003) Interactions of sanguinarine and chelerythrine with molecules containing a mecapto group. J Phys Org Chem 16:803-810.
Kosina P, Ševčík J, Modrianský M, Gavenda A, Bednář P, Barták P, Walterová D, Ulrichová J (2003) High performance liquid chromatography and capillary electrophoresis determination of sanguinarine in biological matrices. J Sep Sci 26:679-685.
Šedo A, Malík R, Vičar J, Šimánek V, Ulrichová J (2003) Quarternary Benzo[c]phenanthridine Alkaloids as Inhibitors of Dipeptidyl Peptidase IV-Like Activity Bearing Enzymes in Human Blood Plasma and Glioma Cell Lines. Physiol Res 52:367-372.
Šimánek V., Vespalec R., Šedo A., Ulrichová J., Vičar J.: Quaternary Benzo/c/phenanthridine alkaloids – biological activities. In: Schneider M.P. (ed.), Chemical probes in biology. Netherlands, Kluwer Academic Publishers 2003, pp. 245-254.
Dvořák Z, Kosina P, Walterová D, Šimánek V, Bachleda P, Ulrichová J (2003) Primary cultures of human hepatocytes as a tool in cytotoxicity studies: cell protection against model toxins by flavonolignans obtained from Silybum marianum. Toxicol Lett 137:201-212.
Škottová N, Ulrichová J, Křen V, Urbaníková J, Šimánek V (2003) Flavonoidy silymarinu a polynenasycené mastné kyseliny rybízového oleje jako nutraceutikum v prevenci chronických onemocnění. Prakt Lék 83, 444-450.
Svagera Z, Skottova N, Vana P, Vecera R, Urbanek K, Belejova M, Kosina P, Simanek V (2003) Plasma lipoproteins in transport of silibinin, an antioxidant flavonolignan from Silybum marianum. Phytother Res 17:524-530.
Skottova N, Vecera R, Urbanek K, Vana P, Walterova D, Cvak L (2003) Effects of polyphenolic fraction of silymarin on lipoprotein profile in rats fed cholesterol-rich diets. Pharmacol Res 47:17-26.
Vecera R, Skottova N, Vana P, Kazdova L, Chmela Z, Svagera Z, Walterova D, Ulrichova J, Simanek V (2003) Antioxidant status, lipoprotein profile and liver lipids in rats fed on high-cholesterol diet containing currant oil rich in n-3 and n-6 polyunsaturated fatty acids. Physiol Res 52:177-187.
Svobodová A, Psotová J, Walterová D (2003) Natural phenolics in the prevention of UV-induced skin damage. A review. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 147:137-145.
Psotova J, Kolar M, Sousek J, Svagera Z, Vicar J, Ulrichova J (2003) Biological activities of Prunella vulgaris extract. Phytother Res 17:1082-1087.
Psotová J, Lasovský J, Vičar J (2003) Metal-chelating properties, electrochemical behavior, scavenging and cytoprotective activities of six natural phenolics. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 147:147-153.
Simonovska B, Vovk I, Andrenšek S, Valentová K, Ulrichová J (2003) Investigation of phenolic acids in yacon (Smallanthus sonchifolius) leaves and tubers. J Chromatogr A 1016:89-98.
Valentová K, Cvak L, Muck A, Ulrichová J, Šimánek V (2003) Antioxidant activity of extracts from the leaves of Smallanthus sonchifolius. Eur J Nutr 42:61-66.
Jirovský D, Horáková D, Kotouček M, Valentová K, Ulrichová J (2003) Analysis of phenolic acids in plant materials using HPLC with amperomemetric detection at a platinum tubular electrode. J Sep Sci 26:739-742.
Lebeda A, Doležalová I, Valentová K, Dziechciarková M, Greplová M, Opatová H, Ulrichová J (2003) Biologická a chemická variabilita maky a jakonu. Chem Listy 97:548-556.
2003-18
Stejskal D, Dvořáčková S, Volný T, Bartek J, Večeřa R, Škottová N, Šimánek V: Combination of silymarin with yacon (Smallanthus sonchifolius) as a prospective nutraceutical. In: Eklund T., DeBrabander H., Daeseleire E., Dirinck I., Ooghe W. (eds.), Strategies for safe food. KVCV Centraal, Heverlee 2003, vol. 2, pp. 741-744.
2003-19
Valentová K, Ulrichová J (2003) Smallanthus sonchifolius and Lepidium meyenii – prospective Andean crops for the prevention of chronic diseases. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 147:119-130.
Dvořák Z, Modrianský M, Pichard-Garcia L, Balaguer P, Vilarem MJ, Ulrichová J, Maurel P, Pascussi JM (2003) Colchicine Down-Regulates Cytochrome P450 2B6, 2C8, 2C9, and 3A4 in Human Hepatocytes by Affecting Their Glucocorticoid Receptor-Mediated Regulation. Mol Pharmacol 64:160-169.
Pascussi JM, Dvořák Z, Gerbal-Chaloin S, Assenat E, Maurel P, Vilarem MJ (2003) Pathophysiological Factors Affecting CAR Gene Expression. Drug Metab Rev 35:255-268.
Ellington E, Bastida J, Viladomat F, Šimánek V, Codina C (2003) Occurence of colchicine derivatives in plants of the genus Androcymbium. Biochemical Systematics and Ecology 31:715-722.
2003-23
Anzenbacherová E, Filipová K, Nobilis M, Anzenbacher P (2003) Selective determination of famotidine in human plasma by high performance liquid chromatography in alkaline media with solid phase extraction. J Sep Sci 26:722-726.
Chlup R, Mlčák P, Boudová E, Fialová J, Bartek J (2003) Kontinuální monitorování koncentrace glukosy v intersticiální tekutině – naše první zkušenosti. Klin Biochem Metab 11:37-43.
Mlčák P, Chlup R, Boudová E, Bartek J, Zapletalová J (2003) Vývoj koncentrace glukosy v intersticiální tekutině u nediabetiků s ohledem na detekci fenoménu svítání – pilotní studie. Klin Biochem Metab 11:44-49
Modrianský M, Valentová K, Přikrylová V, Walterová D (2003) Přírodní látky v prevenci onemocnění trávícího traktu. Chem Listy 97:540-547.
Dvořák Z, Pascussi JM, Modrianský M (2003) Approaches to messenger RNA detection – comparison of methods. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 147:131-135.
Stejskal D, Bartek J (2003) Adiponectin in patients with various stages of coronary heart disease – comparison of its concentration in coronary arteries and peripheral venous cicrulation. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 147:161-166.
Stejskal D, Růžička V, Adamovská S, Juráková R, Prošková J, Jedelský L, Bartek J (2003) Adiponectin concentrations as a criterion of metabolic control in persons with Type 2 diabetes mellitus?. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 147:167-172.
| 2004 |
2004-01
Kosina P, Walterová D, Ulrichová J, Lichnovský V, Stiborová M, Rýdlová H, Vičar J, Krečman V, Brabec MJ, Šimánek V (2004) Sanguinarine and chelerythrine: assessment of safety on pigs in ninety days feeding experiment. Food Chem Toxicol 42:85-91.
2004-02
Vrba J, Hrbáč J, Ulrichová J, Modrianský M (2004) Sanguinarine is a potent inhibitor of oxidative burst in DMSO-differentiated HL-60 cells by a non-redox mechanism. Chem-Biol Interact 147:35-47.
2004-03
Vrba J, Kosina P, Ulrichova J, Modriansky M (2004) Involvement of cytochrome P450 1A in sanguinarine detoxication. Toxicol Lett 151:375-387.
Adámková H, Vičar J, Palasová J, Ulrichová J, Šimánek V (2004) Macleya cordata and Prunella vulgaris in oral hygiene products – their efficacy in the control of gingivitis. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 148:103-105.
Šimánek V, Zdařilová A, Ulrichová J (2004) Sanguinarine and chelerythrine: Chemical behaviour and biological activities. Ann Pol Chem Soc 3:613-616.
Chlopcikova S, Psotova J, Miketova P, Simanek V (2004) Chemoprotective effect of plant phenolics against anthracycline-induced toxicity on rat cardiomyocytes. Part I. Silymarin and its flavonolignans. Phytother Res 18:107-110.
Chlopcikova S, Psotova J, Miketova P, Sousek J, Lichnovsky V, Simanek V (2004) Chemoprotective effect of plant phenolics against anthracycline-induced toxicity on rat cardiomyocytes Part II. caffeic, chlorogenic and rosmarinic acids. Phytother Res 18:408-413.
Psotova J, Chlopcikova S, Miketova P, Hrbac J, Simanek V (2004) Chemoprotective effect of plant phenolics against anthracycline-induced toxicity on rat cardiomyocytes. Part III. Apigenin, baicalelin, kaempherol, luteolin and quercetin. Phytother Res 18:516-521.
2004-09
Gazak R, Svobodova A, Psotova J, Sedmera P, Prikrylova V, Walterova D, Kren V (2004) Oxidised derivatives of silybin and their antiradical and antioxidant activity. Bioorg Med Chem 12:5677-5687.
Valentová K, Moncion A, deWaziers I, Ulrichová J (2004) The effect of Smallanthus sonchifolius leaf extracts on rat hepatic metabolism. Cell Biol Toxicol 20:109-120.
Pascussi JM, Dvořák Z, Gerbal-Chaloin S, Assenat E, Drocourt L, Maurel P, Vilarem MJ. Regulation Of xenobiotic detoxification by PXR, CAR, GR, VDR and SHP receptors: Consequences in physiology. In: Gossen M, Kaufmann J, Triezenberg SJ, editors. Handbook of Experimental Pharmacology, Vol 166, Transcription Factors. Springer-Verlag 2004. p 409-35.
Dvořák Z., Maurel P., Ulrichová J., Modrianský M. (2004) Microtubule disarray in primary cultures of human hepatocytes inhibits transcriptional activity of the glucocorticoid receptor via activation of c-jun N-terminal kinase. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 148:135-139.
Vrba J., Modriansky M. (2004) N-Formyl-Met-Leu-Phe-induced oxidative burst in DMSO-differentiated HL-60 cells requires active hsp90, but not intact microtubules. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 148:141-144.
2004-14
Dvořák Z., Modrianský M., Ulrichová J., Maurel P. (2004) Speculations on the role of the microtubule network in glucocorticoid receptor signaling. Cell Biol Toxicol 20:333-343.
Micuda S, Mundlova L, Anzenbacherova E, Anzenbacher P, Chladek J, Fuksa L, Martinkova J (2004) Inhibitory effects of memantine on human cytochrome P450 activities: prediction of in vivo drug interactions. Eur J Clin Pharmacol 60:583-589.
Kousalova L, Anzenbacherova E, Baranova J, Anzenbacher P, Skoumalova I, Vondrakova J (2004) Presence of cytochrome P450 enzymes in human CD34+ haematopoietic progenitor cells. Gen Physiol Biophys 23:251-257.
Jenett-Siems K, Kohler I, Kraft C, Pertz HH, Kren V, Fiserova A, Kuzma M, Ulrichova J, Bienzle U, Eich E (2004) In vitro antiplasmodial activities of semisynthetic N,N'-spacer-linked oligomeric ergolines. Bioorg Med Chem 12:817-824.
Stejskal D, Horák P, Balíková R, Juránková R, Adamovská S, Jedelský L, Prošková J, Lačňák B, Bartek J (2004) Vlastní zkušenosti s využitím analýzy protilátek proti alfa-fodrinu u pacientů se Sjogrenovým syndromem. Klin Biochem Metab 12:88-91.
Vrzal R, Ulrichová J, Dvořák Z (2004) Aromatic hydrocarbon receptor status in the metabolism of xenobiotics under normal and pathophysiological conditions. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 148:3-10.
Chlup R, Bartek J, Řezníčková M, Zapletalová J, Doubravová B, Chlupová L, Sečkař P, Dvořáčková S, Šimánek V (2004) Determination of glycaemic index of selected foods (white bread and cereal bars) in healthy persons. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 148:17-25.
Valentová K., Entnerová P., Urbaníková J., Šimánek V. (2004) Chemie mužské sexuality. Chem Listy 98:1119-1129.
Janiczek O, Glatz Z, Wimmerova M, Psotova J (2004) Purification and some properties of isocitrate dehydrogenase from Paracoccus denitrificans. Prep Biochem Biotechnol 34:279-289.
| 2005 |
2005-01
Vlčková M, Kubáň, Vičar J, Šimánek V (2005) Electrophoretic studies of interactions of some quaternary isoquinoline alkaloids with DNA and DNA constituents. Electrophoresis 26: 1673-1679.
2005-02
Zajoncova L., Kosina P., Vicar J.,Ulrichova J., Pec P. (2005) Study of the Inhibition of α-Amylase by Benzo[c]phenanthridine Alkaloids Sanguinarine and Chelerythrine. J Enzyme Inhib 20:261-267.
2005-03
Vrzal R., Zdarilova A., Ulrichova J., Blaha L., Giesy J.P., Dvorak Z. (2005) Activation of Aryl Hydrocarbon receptor by berberine in HepG2 cells and H4IIE cells: Biphasic effect on CYP1A1. Biochem Pharmacol 70:925-936.
2005-04
Kosina P, Maurel P, Ulrichová J, Dvořák Z (2005) Effect of silybin and its glycosides on the expression of cytochromes P450 1A2 and 3A4 in primary cultures of human hepatocytes. J Biochem Mol Toxicol 19:149-153.
2005-05
Kren V, Walterova D (2005) Silybin and silymarin – New effects and applications. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 149:29-41.
Psotova J, Chlopcikova S, Miketova P, Simanek V (2005) Cytoprotectivity of Prunella vulgaris on doxorubicin-treated rat cardiomyocytes. Fitoterapia 76:556-561.
2005-07
Pliskova M, Vondracek J, Kren V, Gazak R, Sedmera P, Walterova D, Psotova J, Simanek V, Machala M (2005) Effects of silymarin flavonolignans and synthetic silybin derivatives on estrogen and aryl hydrocarbon receptor activation. Toxicology 215:80-89.
2005-08
Valentova K., Sersen F., Ulrichova J. (2005) Radical Scavenging and Anti-Lipoperoxidative Activities of Smallanthus sonchifolius Leaf Extracts. J Agric Food Chem 53(14):5577-5582.
Dvořák Z, Modrianský M, Ulrichová J, Maurel P, Vilarem MJ, Pascussi JM (2005) Disruption of microtubules leads to glucocorticoid receptor degradation in HeLa cell line. Cell Signal 17:187-196.
2005-10
Ruzicka M, Skobisova E, Dlaskova A, Santorova J, Smolkova K, Spacek T, Zackova M, Modriansky M, Jezek P (2005) Recruitment of mitochondrial uncoupling protein UCP2 after lipopolysaccharide induction. Int J Biochem Cell Biol 37:809-821.
2005-11
Skvarilova M, Bulava A, Stejskal D, Adamovska S, Bartek J (2005) Increased level of advanced oxidation products (AOPP) as a marker of oxidative stress in patiens with acute coronary syndrome. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 149:83-87.
2005-12
Stejskal D, Lacnak B, Andelova K, Skvarilova M, Bartek J (2005) MLC-1 (Myosám Light Chains-1) in differential diagnosis of dyspnea. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 149:89-91.
2005-13
Stejskal D, Ruzicka V, Fanfrdlova G, Kolar V, Bartek J (2005) High adiponectin and TNF-a levels in moderate drinkers suffering from liver steatosis: Comparison with non-drinkers suffering from similar hepatopathy. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 149:93-99.
2005-14
Šimánek V, Kren V, Ulrichova J, Gallo J (2005) The efficacy of glucosamine and chondroitin sulfate in the treatments of osteoarthritis: Are these saccharides drugs or nutraceuticals? Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 149:51-56.
2005-15
Anzenbacherová E, Baranová J, Zuber R, Pěchová A, Anzenbacher P, Souček P, Martínková J (2005) Model systems based on experimental animals for studies on drug metabolism in man: Minipig cytochromes P450 CYP3A29 and 2E1. Basic Clin Pharmacol Toxicol 96:244-245.
2005-16
Dvořák Z, Modrianský M, Šimánek V, Ulrichová J, Vičar J, Vrba J, Walterová D (2005) Sanguinarine activates polycyclic aromatic hydrocarbon associated metabolic pathways in human oral keratinocytes and tissues. Toxicol Lett 158:164-165.
2005-17
Frycak P, Zdrahal Z, Ulrichova J, Wiegrebe W, Lemr K (2005) Evidence of covalent interaction of fumaric acid esters with sulfhydryl groups in peptides. J Mass Spectrom 40:1309-1318.
2005-19
Modrianský M., Dvořák Z. (2005) Microtubule disruptors and their interactions with biotransformation enzymes. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 149:213-215.
Anzenbacherová E, Hudeček J, Murgida D, Hildebrandt P, Marchal S, Lange R, Anzenbacher P. (2005) Active sites of two orthologous cytochromes P450 2E1: differences revealed by spectroscopic methods. Biochem Biophys Res Commun 338:477-482.
Hrbáč J, Broncová G, Matějka P, Bystroň T, Vrba J, Volf R, Vičar J (2005) Electrochemistry of Benzophenanthridine Alkaloids. Formation and Characterization of Redox Active Films from Products of Sanguinarine and Chelerythrine Oxidation. Electroanalysis 17:2175-2181.
| 2006 |
Zdařilová A., Vrzal R., Rypka M., Ulrichová J., Dvořák Z. (2006) Investigation of sanguinarine and chelerythrine effects on CYP1A1 expression and activity in human hepatoma cells. Food Chem Toxicol 44:242-249.
Psotová J., Klejdus B., Večeřa R., Kosina P., Kubáň V., Vičar J., Šimánek V., Ulrichová J. (2005) Liquid chromatographic – mass spectrometric evidence of dihydrosanguinarine as a first metabolite of sanguinarine transformation in rat. J Chromatogr B Analyt Technol Biomed Life Sci 830:165-172.
2006-03
Dvořák Z., Vrzal R., Maurel P., Ulrichová J. (2006) Differential effects of selected natural compounds with anti-inflammatory activity on the glucocorticoid receptor and NF-kB in HeLa cells. Chem-Biol Interact 159:117-128.
2006-04
Zdařilová A., Malíková J., Dvořák Z., Ulrichová J., Šimánek V. (2006) Kvartérní isochinolinové alkaloidy sanguinarin a chelerythrin. Učinky in vitro a in vivo. Chem Listy 100:30-41.
2006-05
Valentová K., Lebeda A., Doležalová I., Jirkovský D., Simonovska B., Vosk I., Kosina P., Gasmanová N., Dziechciarková M., Ulrichová J. (2006) The biological and chemical variability of Yacon. J Agric Food Chem 54:1347-1352.
2006-06
Dvořák Z., Vrzal R., Ulrichová J. (2005) Silybin and dehydrosilybin inhibit cytochrome P450 1A1 catalytic activity: Study in human keratinocytes and human hepatoma cells. Cell Biol Toxicol 22:81-90.
2006-07
Valentová K., Buckiová D., Křen V., Pěknicová J., Ulrichová J., Šimánek V. (2006) The in vitro biological activity of Lepidium meyenii extracts. Cell Biol Toxicol 22:91-99.
2006-08
Dvořák Z., Vrzal R., Ulrichová J., Pascussi J.M., Maurel P., Modrianský M. (2006) Involvement of cytoskeleton in AhR-dependent CYP 1A1 expression. Curr Drug Metab 7:301-313.
2006-09
Chlup R., Jelenová D., Kudlová P., Chlupová K., Bartek J., Zapletalová J., Langová K., Chlupová L. (2006) Continuous glucose monitoring – a novel approach to the determination of the glycaemic index of foods (DEGIF 1) - determination of the glycaemic index of foods by means of the CGMS. Exp Clin Endocrinol Diabetes 114:68-74.
2006-10
Džubák P., Hajdúch M., Gažák R., Svobodová A., Psotová J., Walterová D., Sedmera P, Křen V. (2006) New derivatives of silybin and 2,3-dehydrosilybin and their cytotoxic and P-glycoprotein modulatory activity. Bioorg Med Chem 14(11):3793-3810.
2006-11
Psotová J., Večeřa R., Zdařilová A., Anzenbacherová E., Kosina P., Svobodová A., Hrbáč J., Jirovský D., Stiborová M., Lichnovský V., Vičar J., Šimánek V., Ulrichová J. (2006) Safety assessment of sanguiritrin alkaloid fraction of Macleya cordata in rats. Veterinární Medicína 51(4):145-155.
2006-12
Dvořák Z., Sovadinová I., Bláha L., Giesy J.P., Ulrichová J. (2006) Quaternary benzo[c]phenathridine alkaloids sanguinarine and chelerythrine do not affect transcriptional activity of aryl hydrocarbon receptor: Analyses in rat hepatoma cell line H4IIE.luc. Food Chem Toxicol 44:1466-1473.
2006-13
Dvořák Z., Zdařilová A., Šperlíková L., Anzenbacherová E., Šimánek V., Ulrichová J. (2006) Cytotoxicity of sanguinarine in primary rat hepatocytes is attenuated by dioxin and phenobarbital. Toxicol Lett 165:282-288.
2006-14
Psotová J., Svobodová A., Kolářová H., Walterová D. (2006) Photoprotective properties of Prunella vulgaris and rosmarinic acid on human keratinocytes. J Photochem Photobiol B 84(3):167-74.
2006-15
Modrianský M., Ulrichová J., Dvořák Z. (2006) Microtubules and commuting receptors. Letters in Drug Design & Discovery 3(8):567-568.
2006-16
Dvořák Z., Modrianský M., Pascussi JM, Vilarem MJ, Maurel P, Ulrichova J. Microtubules network in glucocorticoid receptor and aryl hydrocarbon receptor signaling. In: Leeds D.T., editor. Focus on Cellular Signaling Research, Nova Science Publisher, Inc., New York 2006, pp 29-54. ISBN 1-59454-619-3.
2006-17
Chlup R., Zapletalová J., Jelenová D., Chlupová K., Bartek J., Řehořová J. (2006) Glykemický index hořké čokolády, ovocného jogurtu, jablečné přesnídávky a rýžových chlebíčků u zdravých. Diabetes a Obezita 6(11):103-112.
2006-18
Dvořák Z., Kubáň V., Klejdus B., Hlaváč J., Vičar J., Ulrichová J., Šimánek V. (2006) Quaternary benzo[c]phenanthridines sanguinarine and chelerythrine: A review of investigations from chemical and biological studies. Heterocycles 68(11):2403-2422.
2006-19
Malíková J., Zdařilová A., Hlobilková A., Ulrichová J. (2006) The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine. Cell Biol Toxicol 22:439-453.
2006-20
Malíková J., Zdařilová A., Hlobilková A. (2006) Effects of sanguinarine and chelerythrine on the cell cycle and apoptosis. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 150(1):5-12.
2006-21
Svobodová A., Walterová D., Vostálová J. (2006) Ultraviolet light induced alteration to the skin. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 150(1):25-38.
2006-22
Svobodová A., Walterová D., Psotová J. (2006) Influence of silymarin and its flavonolignans on H(2)O(2)-induced oxidative stress in human keratinocytes and mouse fibroblasts. Burns 32(8):973-979.
2006-23
Zídek Z., Anzenbacher P., Anzenbacherová E., Buchar E., Kmoníčková E., Potměšil P., Holý A. (2006) In vivo effects of antiviral acyclic nucleoside phosphonate 9-[2-(phosphonomethoxy)ethyl]adenine (adefovir) on cytochrome P450 system of rat liver microsomes. J Biomed Sci 13:295-301.
2006-24
Nekvindová J., Mašek V., Veinlichová A., Anzenbacherová E., Anzenbacher P., Zídek Z., Holý A. (2006) Inhibition of human microsomal cytochrome P450 activities by adefovir and tenofovir. Xenobiotica 36(12):1165-1177.
2006-25
Matal J., Orsag J., Nekvindová J., Anzenbacherová E., Veinlichová A., Anzenbacher P., Zídek Z., Holý A. (2006) Experimental approaches to studies on drug metabolism and drug interactions in man: interaction of acyclic nucleoside phosphonates with human liver cytochromes P450 and flavin-containing monooxygenase 3. Neuro Endocrinol Lett 27(Suppl2):27-30.
| 2007 |
2007-01
Valentová K., Ulrichová J., Cvak L., Šimánek V. (2007) Cytoprotective effect of a bilberry extract against oxidative damage of rat hepatocytes. Food Chem 101: 912-917.
2007-02/03
Dvořák Z., Maurel P., Vilarem M.J., Ulrichová J., Modrianský M. (2007) Expression and transcriptional activities of nuclear receptors involved in regulation of drug metabolizing enzymes are not altered by colchiceine: Focus on PXR, CAR and GR in primary human hepatocytes. Cell Biol Toxicol 23(2):63-73. (Erratum p.141)
2007-04
Dvořák Z. and Šimánek V. (2007) Metabolism of Sanguinarine: The Facts and The Myths. Curr Drug Metab 8(2):173-176.
2007-05
Dvořák Z., Vrzal R., Ulrichová J., Macejová D., Ondková S., Brtko J. (2007) Expression, protein stability and transcriptional activity of retinoic acid receptors are affected by microtubules interfering agents and all-trans retinoic acid in primary rat hepatocytes. Mol Cell Endocrinol 267:89-96.
2007-06
Valentová K., Stejskal D., Bednář P., Vostálová J., Číhalík Č., Večeřová R., Koukalová D., Kolář M., Reichenbach R., Škňouřilová L., Ulrichová J., Šimánek V.(2007): Biosafety, antioxidant status and metabolites in urine after consumption of dried cranberry juice in healthy women: A pilot double-blind placebo controlled trial. J Agric Food Chem 55:3217-3224.
2007-07
Klejdus B., Lojková L., Kosina P., Ulrichová J., Šimánek V., Kubáň V. (2007) Liquid chromatographic/electrospray mass spectrometric determination (LC/ESI-MS) of chelerythrine and dihydrochelerythrine in near-critical CO2 extracts from real and spiked plasma samples. Talanta 72:1348-1356.
2007-08
Večeřa R., Klejdus B., Kosina P., Orolin J., Stiborová M., Smrček S., Vičar J., Dvořák Z., Ulrichová J., Kubáň V., Anzenbacher P., Šimánek V. (2007) Disposition of sanguinarine in the rat. Xenobiotica 37(5):549-558.
2007-09
Gažák R., Walterová D., Křen V. (2007) Silybin and silymarin--new and emerging applications in medicine. Curr Med Chem 14(3):315-38.
2007-10
Červený L., Švecová L., Anzenbacherová E., Vrzal R., Štaud F., Dvořák Z., Ulrichová J., Anzenbacher P., Pávek P. (2007) Valproic acid induces CYP3A4 and MDR1 genes expression by activation of Constitutive androstane receptor and Pregnane X receptor pathways. Drug Metab Dispos 35(7):1032-1041.
2007-11
Dvořák Z., Ulrichová J., Weyhenmeyer R., Šimánek V. (2007) Cytotoxicity of colchicine derivatives in primary cultures of human hepatocytes. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 151(1):47-52.
2007-12
Vashishta A., Ohri S.S., Větvičková J., Fusek M., Ulrichová J., Větvička V. (2007) Procathepsin D secreted by HaCaT keratinocyte cells – A novel regulator of keratinocyte growth. Eur J Cell Biol 86:303-313.
2007-13
Pávek P., Červený L., Švecová L., Brysch M., Libra A., Vrzal R., Štaud F., Ulrichová J., Fendrich Z., Dvořák Z. (2007) Examination of Glucocorticoid receptor α –mediated transcriptional regulation of P-glycoprotein, CYP3A4 and CYP2C9 genes in several placental trophoblast cell lines. Placenta 28(10):1004-1011.
2007-14
Jirovský D, Kosina P, Myslínová M, Stýskala J, Ulrichová J, Šimánek V. (2007) HPLC Analysis of Rosmarinic Acid in Feed Enriched with Aerial Parts of Prunella vulgaris and Its Metabolites in Pig Plasma Using Dual-Channel Coulometric Detection. J Agric Food Chem. 55(19):7631-7637.
2007-15
Valentová K, Truong NT, Moncion A, de Waziers I, Ulrichová J (2007) Induction of glucokinase mRNA by dietary phenolic compounds in rat liver cells in vitro. J Agric Food Chem. 55(19):7726-31.
2007-16
Cvek B., Dvořák Z. (2007) Targeting of Nuclear Factor-kB and Proteasome by Dithiocarbamate Complexes with Metals. Curr Pharm Des 13(30): 3155-3167.
2007-17
Dvořák Z., Modrianský M., Vrba J., Ulrichová J., Kryštof V., Stýskala J., Pávek P. (2007) Evaluation of novel microtubules interfering agents myoseverin, tubulyzine and E2GG in primary cultures of rat hepatocytes. Gen Physiol Biophys 26:173-180.
2007-18
Macejová D., Dvořák Z., Vrzal R., Ulrichová J., Ondková S., Brtko J. (2007) The effect of all-trans retinoic acid and/or colchicine on expression of rexinoid and thyroid hormone nuclear receptors and thein coregulators in primary rat hepatocytes Gen Physiol Biophys 26: 240–242.
2007-19
Svobodová A., Zdařilová A., Mališková J., Mikulková H., Walterová D., Vostálová J. (2007) Attenuation of UVA-induced damage to human keratinocytes by silymarin. J Dermatol Sci 46, 21—30.
2007-20
Svobodová A., Zdařilová A., Walterová D., Vostálová J. (2007) Flavonolignans from Silybum marianum moderate UVA-induced oxidative damage to HaCaT keratinocytes. J Dermatol Sci 48, 213—224.
2007-21
Vrzal R., Ulrichová J., Dvořák Z., Pávek P. (2007) Glucocorticoid receptor functions in HeLa cells are perturbed by 2,3,8,9-tetrachlorodibenzo-p-dioxin (TCDD). Drug Metab Lett 1(4):311-314.
2007-22
Stýskala J., Cankař P., Soural M., Hlaváč J., Hradil P., Vičar J., Šimánek V. (2007) Synthesis of isodecarine. Heterocycles 73:769 - 775.
2007-23
Hudecek J., Hodek P., Anzenbacherova E., Anzenbacher P. (2007) Sructural analysis of cytochromes P450 shows differences in flexibility of heme 2- and 4-vinyls. Biochim Biophys Acta 1770(3):413-419.
2007-24
Otyepka M., Skopalik J., Anzenbacherova E., Anzenbacher P. (2007) What common structural features and variations of mammalian P450s are known to date? Biochim Biophys Acta 1770(3):376-389.
2007-25
Jancova P., Anzenbacherova E., Papouskova B., Lemr K., Luzna P., Veinlichova A., Anzenbacher P., Simanek V. (2007) Silybin is metabolized by cytochrome P450 2C8 in vitro. Drug Metab Dispos 35(11):2035-2039.
2007-26
Papouskova B., Bednar P., Frysova I. Styskala J., Hlavac J., Bartak P., Ulrichova J., Jirkovsky J., Lemr K. (2007) Mass spectrometric study of selected precursors and degradation products of chemical warfare agents. J Mass Spectrom 42:1550–1561.
2007-27
Švarcová I., Heinrich J., Valentová K. (2007) Berry fruits as a source of biologically active compounds: The case of Lonicera caerulea. Biomed. Pap. 151 (2), 163 – 174.
| 2008 |
2008-01
Dvorak Z., Vrzal R., Henklova P., Jancova P., Anzenbacherova E., Maurel P., Svecova L., Pavek P., Ehrmann J., Havlik R., Bednar P., Lemr K., Ulrichova J. (2008) JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes. Biochem Pharmacol 75(2):580-588.
2008-02
Vrba J., Dvorak Z., Ulrichova J., Modriansky M. (2008) Conventional protein kinase C isoenzymes undergo dephosphorylation in neutrophil-like HL-60 cells treated by chelerythrine or sanguinarine. Cell Biol Toxicol 24(1):39-53.
2008-03
Valentová K., Stejskal D., Bartek J., Dvořáčková S., Křen V., Ulrichová J., Šimánek V. (2008) Maca (Lepidium meyenii) and yacon (Smallanthus sonchifolius) in combination with silymarin as food supplements: In vivo safety assessment. Food Chem Toxicol. 46, 1006-1013.
2008-04
Vrzal
R., Daujat-Chavanieu M., Pascussi J.M., Ulrichova J., Maurel P., Dvorak
Z. (2008) Microtubules-interfering agents restrict aryl
hydrocarbon receptor-mediated CYP1A2 induction in primary cultures of
human hepatocytes via c-jun-N-terminal kinase and glucocorticoid
receptor. Eur J Pharmacol 581:244-254.
2008-05
Trouillas P., Marsal P., Svobodova A., Vostalova J., Gazak R., Hrbac J., Sedmera P., Kren V., Lazzaroni R., Duroux J.L., Walterova D. (2008) Mechanism of the Antioxidant Action of Silybin and 2,3-Dehydrosilybin Flavonolignans: A Joint Experimental and Theoretical Study. J Phys Chem A 112:1054-1063.
2008-06
Pavek P. and Dvorak Z. (2008) Xenobiotic-Induced Transcriptional Regulation of Xenobiotic Metabolizing Enzymes of the Cytochrome P450 Superfamily in Human Extrahepatic Tissues. Curr Drug Metab 9(2):129-143.
2008-07
Svecova
L., Vrzal R., Burysek L., Anzenbacherova E., Cerveny L., Grim J.,
Trejtnar F., Kunes J., Pour M., Staud F., Anzenbacher P., Dvorak Z.,
Pavek P. (2008) Azole antimycotics
differentially affect rifampicin-induced Pregnane X Receptor
(PXR)-mediated CYP3A4 gene expression. Drug Metab Dispos
36(2):339-348.
2008-08
Henklova
P., Vrzal R., Ulrichova J., Dvorak Z.
(2008) Role of
mitogen-activated protein
kinases in aryl hydrocarbon receptor signaling.
Chem-Biol Interact 72:93-104.
Anzenbacher P., Anzenbacherová E., Lange R., Skopalík J., Otyepka M. (2008) Active sites of cytochrome P450: What are they like? Acta Chim Slov 55:63-66.
Vrba J., Dolezel P., Vicar J., Modriansky M., Ulrichova J. (2008) Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells. Toxicology in Vitro 22:1008–1017.
Heinrich J., Švarcová I., Valentová K. (2008) Plody Lonicera caerulea: Perspektivní funkční potravina a zdroj biologicky aktivních látek. Chem Listy 102:245-254.
Lebeda A., Dolezalova I., Valentova K., Gasmanova N., Dziechciarkova M., Ulrichova J. (2008) Taxon (Smallanthus sonchifolius) – A traditional crop of Andean indians as a challenge for the future – The news about biological variation and chemical substance content. Acta Hort 765:127-136.
Vrublova
E., Vostalova J., Vecera R., Klejdus B., Stejskal D., Kosina P.,
Zdarilova A.,
Svobodova A., Lichnovsky V., Anzenbacher P., Dvorak Z., Vicar J.,
Simanek V.,
Ulrichova J. (2008) The
toxicity and
pharmacokinetics of dihydrosanguinarine in rat: A pilot study. Food Chem Toxicol 46:2546-2553.
Svobodova A., Rambouskova J., Waltrova D., Vostalova J. (2008) Protective effects of phenolic fraction of blue honeysuckle fruits against UVA-induced damage to human keratinocytes. Arch Dermatol Res 300:225-233.
Dvorak
Z., Vrzal R., Pavek P., Ulrichova J. (2008) An
evidence for regulatory cross-talk between aryl hydrocarbon receptor
and glucocorticoid receptor in HepG2 cells. Physiol
Res 57:427-435.
Valouskova
E., Modriansky M. (2008) Modulation
of UCP2 expression by p38 – a link to
cardioprotection. Biomed Pap
Med Fac Univ Palacky Olomouc Czech
Repub 152:3-7.
Stiborova
M., Vostalova J., Zdarilova A., Ulrichova J., Hudeček J., Tschirner K.,
Šimánek
V. (2008) Macleaya
cordata
extract and Sangrovit® genotoxicity.
Assessment in vivo.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 152:35-39.
2008-18
Bachleda
P. and Dvorak Z. (2008) Pharmacological
inhibitors of JNK and ERK kinases SP600125 and U0126 are not
appropriate tools
for studies of drug metabolism because they activate
aryl hydrocarbon receptor. Gen Physiol Biophys 27:143–146.
Valouskova
E., Smolkova K., Santorova J., Jezek P.,
Modriansky M. (2008) Redistribution of cell death-inducing
DNA fragmentation
factor-like effector-a (CIDEa) from mitochondria to nukleus
is associated with apoptosis in HeLa cells. Gen
Physiol Biophys 27:92-100.
Anzenbacher P., Anzenbacherova E. (2008) Enzyme systems of detoxication – Overview of recent approaches. Interdisc. Toxicol. 1: 6-7.
Cvek
B. and Dvorak Z. (2008) The value of proteasome
inhibition in cancer. Can the old drug, disulfiram, have a bright new
future as
a novel proteasome inhibitor? Drug Discov
Today 13:716-722.
Henklova
P., Vrzal R., Papouskova B., Bednar P., Jancova
P., Anzenbacherova E., Ulrichova J., Maurel P., Pavek P., Dvorak Z. (2008) SB203580, a pharmacological inhibitor
of p38 MAP
kinase transduction pathway activates ERK and JNK MAP kinases in
primary
cultures of human hepatocytes. Eur J
Pharmacol 593:16-23.
Stejskal D., Karpísek M., Humenanska V., Hanulova Z., Stejskal P., Kusnierova P., Petzel M. (2008) Lipocalin-2: development, analytical characterization, and clinical testing of a new ELISA. Horm Metab Res 40:381-385.
Cvek B., Milacic V., Taraba J., Dou Q.P. (2008) Ni(II), Cu(II), and Zn(II) diethyldithiocarbamate complexes show various activities against the proteasome in breast cancer cells. J Med Chem 51:6256-6258.
Cvek
B. (2008) TNF-alpha could be responsible
for disulfiram-mediated hepatotoxicity. J
Hepatol 49:865-866.
Zdarilova A., Vrublova E., Vostalova J., Klejdus B., Stejskal D., Proskova J., Vecera R., Kosina P., Svobodova A., Vecera R., Hrbac J., Cernochova D., Vicar J., Ulrichova J., Simanek V. (2008) Natural feed additive of Macleaya cordata: Safety assessment in rats a 90-day feeding experiment. Food Chem Toxicol 46:3721-3726.
Anzenbacherova
E., Anzenbacher P., Zidek Z., Buchar E.,
Kmonickova E., Potmesil P., Nekvindova J., Veinlichova A., Holy A.
(2008) In vivo study of the effect of antiviral acyclic nucleotide
phosphonate
(R)-9-[2-(phosphonomethoxy)propyl]adenine (PMPA, tenofovir) and its
prodrug
tenofovir disoproxil fumarate on rat microsomal cytochrome
P450.
Physiol Res 57:761-767.
Matal
J.,
Jancova P., Siller M., Masek V., Anzenbacherova E., Anzenbacher P.
(2008) Interspecies comparison of the glucuronidation processes in the
man,
monkey, pig, dog and rat. Neuro
Endocrinol Lett 29:738-743.
Palikova
I., Heinrich J., Bednar P., Marhol P., Kren V.,
Cvak L., Valentova K., Ruzickova F., Hola V., Kolar M., Simanek V.,
Ulrichova
J.
(2008) Constituents and antimicrobial
properties of blue honeysuckle: A novel source for phenolic
antioxidants. J. Agric. Food Chem. 56: 11883-11889.
Onica
T., Nichols K., Larin M., Nq L., Maslen A., Dvorak Z., Pascussi J.M.,
Vilarem
J.M., Maurel P., Kirby G.M. (2008) Dexamethasone-mediated
up-regulation of human CYP2A6 involves the glucocorticoid receptor and
increased binding of hepatic nuclear factor 4 alpha to the proximal
promoter. Mol. Pharmacol.
73:451-460.
Oborna
I., Fingerova H., Novotny J., Svobodova M., Brezinova J., Vostalova, J.
et al.
(2008). Oxidační stres v diagnostice a léčbě
idiopatické mužské neplodnosti. Česká
gynekologie 73: 356-360.
Ayaz FA., Hayirhioglu-Ayaz S., Alpay-Karaoglu S., Gruz, J., Valentova K., Ulrichova J., Strnad M. (2008). Phenolic acid contents of kale (Brassica oleraceae L. var. acephala DC.) extracts and their antioxidant and antibacterial activities. Food Chemistry, 107: 19-25.
Lebeda, A., Doležalová, I., Valentová, K., Gasmanova, N., Dziechciarkova, M. et Ulrichova, J. (2008): Yacon (Smallanthus sonchifolius) - A traditional crop of Andean indians as a challenge for the future – The news about biological variation and chemical substances content. Acta Hort., 765, 127-136.
Solichova P., Karpisek M., Ochmanova R., Hanulova Z., Humenanska V., Stejskal D. (2008). Urinary clusterin concentrations-a possible marker of nephropathy? Pilot study. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 151: 233-236.
| 2009 |
2009-1
2009-2
2009-3
2009-4
2009-5
Franková J., Ulrichová J. (2009) Vliv Traumacelu biodress na produkci matrixových metaloproteináz. Hojení ran 3:4-7.
2009-12
Absolínová H., Jančář L., Jančářová I., Vičar J., Kubáň V. (2009) Acid-base behaviour of sanguinarine and dihydrosanguinarine. Cent. Eur. J. Chem. 7:876-883.
2009-13
Veinlichová A., Jančová P., Šiller M., Anzenbacher P., Kuča K., Jun D., Fusek J., Anzenbacherová E. (2009) Effect of acetylcholinesterase oxime-type reactivators K-48 and HI-6 on human liver microsomal cytochromes P450 in vitro. Chem Biol Interact. 180:449-53.
2009-14
Anzenbacherová E., Anzenbacher P., Tunková A., Adamus M. (2009) Možné interakce rokuronia s jaterními mikrosomálními cytochromy P450. Klin Farmakol Farm. 23: 108-110.
2009-15
Chlup R., Kudlová P., Peterson K.,
Slezáková L., Bartek J.,
Nakládalová M., Sečkař P., Zapletalová
J., Langová K., Táncosová S.,
Doubravová B. (2009) Glykemický
index potravin u osob s diabetem
2009-16
Chlup R., Zapletalová J., Jelenová D., Chlupová K., Bartek J., Řehořová J. ( 2009) Glykemický index hořké čokolády, ovocného jogurtu, jablečné přesnídávky a rýžových chlebíčků u zdravých osob. Interní medicína pro praxi 11 (suppl. B):B83-B86.
Matuskova Z., Tunkova A., Anzenbacherova E., Zidek Z., Tlaskalova-Hogenova H., Anzenbacher P. (2009) Influence of probiotics on rat liver biotransformation enzymes. Neuro Endocrinol Lett. 30(Suppl):41-45.
Matal J., Tunkova A., Šiller M., Anzenbacherová E., Anzenbacher P. (2009) Isolation of two cytochrome P450 forms, CYP2A19 and CYP1A, from pig liver microsomes Journal of Veterinary Pharmacology and Therapeutics 32: 470-476.
2009-19
Matal J., Matuskova Z., Tunkova A., Anzenbacherova E., Anzenbacher P. (2009) Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system. Neuro Endocrinol Lett. 30(Suppl):36-40.
| 2010 |
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Rostislav Večeřa (2000): Sérové triacylglyceroly a intravaskulární remodelování HDL u člověka.
Pavel Kosina (2000): Biologická aktivita glykosidů silybinu.
Helena Marková (2001): Biologická aktivita extraktu a některých obsahových látek Prunella vulgaris.
Zdeněk Dvořák (2001): Primární kultury lidských hepatocytů jako model pro toxikologické studie.
Vladimír Krečman (2002): Studie silymarinu jako antihypercholesterolemika a LDL antioxidantu u potkanů.
Šárka Chlopčíková (2003): Natural phenolics as potential adjuvants in chemotherapy.*
Roman Zuber (2003): Izolace a charakterizace jaterních mikrosomálních cytochromů P450 miniprasete.
Kateřina Valentová (2004): Biologická aktivita andských plodin Smallanthus sonchifolius a Lepidium meyenii.*
Zdeněk Švagera (2004): Biodostupnost, transport a distribuce antioxidačního flavonoidu silibininu u potkana.
David Stejskal (2005): Leptinový receptor.
Dalibor Novotný (2005): Kandidátní geny pro aterosklerózu: analýza u pacientů s různou klinickou manifestací onemocnění.
Jiří Vrba (2005): Mechanismy modulace oxidativního vzplanutí přírodními látkami.*
Alena Svobodová (2006): Effects of natural polyphenols on UV-induced damage to keratinocytes.*
Adéla Zdařilová (2006): Biologická aktivita benzo[c]fenantridinových alkaloidů sanguinarinu a chelerytrinu.*
David Kopečný (2006): Structure and function of cytokinin oxidase / dehydrogenase. Modification of enzymes.
Zbyněk Lamplot (2006): Nové syntetické substráty a inhibitory aminoxidas a polyaminoxidas.
Radim Vrzal (2007): Effect of microtubules-interfering agents on aryl-hydrocarbon receptor signalling (Doctorat en Cotutelle INSERM U632, Montpellier)
Pavlína Solichová (2007): Využití stanovení cystatinu C v diagnostice a monitorování ledvinných funkcí.
Marie Staňková (2007): Možnosti záchytu a stanovení antidepresiv nových generací v biologickém materiálu.
Taťána Štosová (2008): Chemical modifications of trypsin.
Pavla Henklová (2009) Interaction of Mitogen-activated Protein Kinases Inhibitors with AhR-signal Pathway.*Martin Petzel
* Plný text disertační práce je k dispozici u autora/ky./ Full text of the thesis is available on request.