Curriculum vitae

Prof. RNDr. Jitka Ulrichová, CSc.
Date of birth: 9. 11. 1956

Birthplace: Vsetín, Czech Republic

Contact:
Department of Medical Chemistry and Biochemistry
Hnìvotínská 3, 775 15 Olomouc, Czech Republic
Tel.: 420-585 632 312, Fax.: +420-585 632 302
E-mail: jitka.ulrichova@upol.cz, JitkaUlrichova@seznam.cz

Education:

1972 – 1976     Secondary School, Olomouc
1976 – 1981   Biochemistry, Faculty of Science, Masaryk University, Brno
1981 – 1985   PhD in Biochemistry, Medical Faculty, Palacký University, Olomouc
1997   Habilitation, Biochemistry, Pharmaceutical Faculty of Charles University, Hradec Králové
2003   Professor, Medical Faculty, Palacký University, Olomouc

Postdoctoral training:

1990     Scientific stay, École Nationale Supérieure de Chimie de Paris, France
1992   FEBS Advanced Course, Louvain-la-Neuve, Belgium
1995   Scientific stay, MADAUS AG. Koln, Germany
1996   Scientific stay, Institute of Biochemistry, University of Bern, Switzerland
1999, 2000, 2003   Scientific stay, INSERM, Montpellier, France
2001, 2003   Scientific stay National Institute of Chemistry, Ljubljana, Slovenia
2001   School of Medicine, Emory University, Atlanta, U.S.A.

Academic appointments:

1985 - 1996     Professor assistant, Institute of Medical Chemistry, Medical Faculty, Palacký University, Olomouc
1997 - 2003   Associate professor, Institute of Medical Chemistry, Medical Faculty, Palacký University, Olomouc
2003   Professor, Institute of Medical Chemistry, Medical Faculty, Palacký University, Olomouc

Present position and affilation:

Head of the Laboratory of Cell Cultures (from 2002), Medical Faculty, Palacky University, Hnìvotínská 3, 775 15 Olomouc
Head of the Department of Medical Chemistry and Biochemistry (from 2008),  Medical Faculty, Palacky University, Hnìvotínská 3, 775 15 Olomouc
Vice-rector for Science and Research and Statutary Vice-Rector of the Palacký University Olomouc

Membership:

1987     Czech Chemical Society (President since 2006)
1987   Czech Society for Biochemistry and Molecular Biology
1998   American Chemical Society
2000   ESTIV (European Society of Toxicology In Vitro)
2001   ISSX (International Society for Study of Xenobiotics)
2006   Phytochemical Society of Europe

Major interest: Biological activity of natural substances (cytotoxicity, cytoprotectivity),
                       mammalian cell cultures (hepatocytes, fibroblasts, keratinocytes).

PUBLICATIONS: 91 original papers, 26 reviews, 5 Czech patents

Citation index (SCI): 348

Recent publications:

  1. Valentová K., Ulrichová J., Cvak L., Šimánek V. (2007) Cytoprotective effect of a bilberry extract against oxidative damage of rat hepatocytes. Food Chem 101: 912-917. 
  2. Malíková J., Zdaøilová A., Hlobilková A., Ulrichová J. (2006) The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine. Cell Biol Toxicol 22:439-453.
  3. Dvoøák Z., Kubáò V., Klejdus B., Hlaváè J., Vièar J., Ulrichová J., Šimánek V. (2006) Quaternary benzo[c]phenanthridines sanguinarine and chelerythrine: A review of investigations from chemical and biological studies. Heterocycles 68(11):2403-2422.

  4. Dvorak Z., Vrzal R., Henklova P., Jancova P., Anzenbacherova E., Maurel P., Svecova L., Pavek P., Ehrmann J., Havlik R., Bednar P., Lemr K., Ulrichova J. (2008) JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes. Biochem Pharmacol 75(2):580-588.

  5. Vrba J., Dvorak Z., Ulrichova J., Modriansky M. (2008) Conventional protein kinase C isoenzymes undergo dephosphorylation in neutrophil-like HL-60 cells treated by chelerythrine or sanguinarine. Cell Biol Toxicol 24(1):39-53.

     

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