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Mgr. Pavel Kosina, PhD. |
Date of birth:
21. 11. 1971 Birthplace: Olomouc |
Contact:
Institute of Medical Chemistry and Biochemistry
Hněvotínská 3, 775 15 Olomouc, Czech Republic
Tel.: 420-585 632 306, Fax.: +420-585 632 302
E-mail: kosina@tunw.upol.cz
1986-1990 | Secondary Grammar school, Olomouc-Hejčín, Czech Republic | |
1990-1995 | MSc. studies in Analytical chemistry with thesis on "Sorption of s-triazines in soils", Faculty of Science, Palacký University, Olomouc, Czech Republic | |
1995-2000 | Ph.D. studies with Ph.D. thesis on "Biological activity of silybin glycosides", Institute of Medical Chemistry and Biochemistry, Faculty of Medicine, Palacký University, Olomouc, Czech Republic | |
1997 | Study stay (2 months) in INSERM U128, Montpellier, France | |
1999 | Study stay (5 months) in Diabetes Research Group, School of Health Sciences, University of Wolverhampton, UK |
1998-2000 | Researcher, Centre for analytical chemistry of molecular structures, Palacký University, Olomouc | |
2001- | Researcher, Institute of Medical Chemistry and Biochemistry, Palacký University, Olomouc |
1995- | Czech Chemical Society | |
1995- | Czech Society for Biochemistry and Molecular Biology | |
2003- | Society for Medicinal Plant Research (Germany) | |
2006- | Phytochemical Society of Europe |
2000 | Prize for student's scientific publication awarded by Dean of Faculty of Medicine, Palacký University Olomouc for "Antioxidant properties of silybin glycosides." Phytother Res. 16, Suppl 1, S33-9 (2002). |
2000- | Quality manager of the testing laboratory - Laboratory of cell cultures LF UP, which is in accord to ČSN EN ISO/IEC 17025 accredited by Czech institute for accreditation, o.p.s. |
PUBLICATIONS 19 original
papers
28 conference presentations
Citation index (SCI): 61
Jirovský D., Kosina ., Myslínová M., Stýskala J., Ulrichová J., Šimánek V. (2007) HPLC analysis of rosmarinic acid in feed enriched with aerial parts of Prunella vulgaris and its metabolites in pig plasma using dual-channel coulometric detection. J. Agric. Food Chem. 55: 7631-7637.
Večeřa R., Klejdus B., Kosina P., Orolin J., Stiborová M., Smrček S., Vičar J., Dvořák Z., Ulrichová J., Kubáň V., Anzenbacher P., Šimánek V. (2007) Disposition of sanguinarine in the rat. Xenobiotica 37(5):549-558.
Klejdus B., Lojková L., Kosina P., Ulrichová J., Šimánek V., Kubáň V. (2007) Liquid chromatographic/electrospray mass spectrometric determination (LC/ESI-MS) of chelerythrine and dihydrochelerythrine in near-critical CO2 extracts from real and spiked plasma samples. Talanta 72:1348-1356.
Psotová J., Klejdus B., Večeřa R., Kosina P., Kubáň V., Vičar J., Šimánek V., Ulrichová J. (2005) Liquid chromatographic – mass spectrometric evidence of dihydrosanguinarine as a first metabolite of sanguinarine transformation in rat. J Chromatogr B Analyt Technol Biomed Life Sci 830:165-172.
Valentová K., Lebeda A., Doležalová I., Jirkovský D., Simonovska B., Vosk I., Kosina P., Gasmanová N., Dziechciarková M., Ulrichová J. (2006) The biological and chemical variability of Yacon. J Agric Food Chem 54:1347-1352.